Please pray

It is in the middle of the night, Greg and I both up and James has been crying now for 55 minutes. I am waiting for MD Anderson to call me back. We are at a loss for what is going on with him. He had a hard day yesterday-he woke at 5:30am and went to bed at 8:30 pm with no nap and cried a lot. We need your prayers-we feel helpless to know what to do. Thank you.